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Literature summary for 3.5.1.115 extracted from

  • Nicholas, G.M.; Newton, G.L.; Fahey, R.C.; Bewley, C.A.
    Novel bromotyrosine alkaloids: inhibitors of mycothiol S-conjugate amidase (2001), Org. Lett., 3, 1543-1545.
    View publication on PubMed
Search for more literature for 3.5.1.115

Inhibitors

Inhibitors Comment Organism Structure
(2Z)-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-N-(4-carbamimidamidobutyl)-2-(hydroxyimino)propanamide
-
 Mycobacterium tuberculosis
(2Z)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-3-[4-(3-aminopropoxy)-3,5-dibromophenyl]-2-(hydroxyimino)propanamide
-
 Mycobacterium tuberculosis
(5R,10S)-N-[2-(2-amino-1H-imidazol-5-yl)ethyl]-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
-
 Mycobacterium tuberculosis
(5R,10S)-N-[2-[2-amino-4-(3,5,8-trihydroxy-4-oxo-1,4-dihydroquinolin-6-yl)-1H-imidazol-5-yl]ethyl]}-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide strongest inhibitor Mycobacterium tuberculosis
3,5,8-trihydroxyquinolin-4(1H)-one
-
 Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a mycothiol S-conjugate + H2O Mycobacterium tuberculosis
-
 an N-acetyl L-cysteine-S-conjugate + 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a mycothiol S-conjugate + H2O
-
 Mycobacterium tuberculosis an N-acetyl L-cysteine-S-conjugate + 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol
-
 ?

Synonyms

Synonyms Comment Organism
MCA
-
 Mycobacterium tuberculosis