Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.103 extracted from

  • McCarthy, A.A.; Knijff, R.; Peterson, N.A.; Baker, E.N.
    Crystallization and preliminary X-ray analysis of N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis (2003), Acta Crystallogr. Sect. D, 59, 2316-2318.
    View publication on PubMed
Search for more literature for 3.5.1.103

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli both in native and SeMet-substituted forms Mycobacterium tuberculosis

Crystallization (Commentary)

Crystallization (Comment) Organism
crystals prepared in the presence of beta-octylglucoside as a key additive, are suitable for high-resolution X-ray structural analysis. The crystals are orthorhombic, with unit-cell parameters a = 71.69, b = 83.74, c = 95.65 A, space group P2(1)2(1)2(1) and two molecules in the asymmetric unit. Collection of X-ray diffraction data to 1.9 A resolution Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O Mycobacterium tuberculosis step in mycothiol biosynthesis 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O Mycobacterium tuberculosis H37Rv step in mycothiol biosynthesis 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WJN3
-
-
Mycobacterium tuberculosis H37Rv P9WJN3
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O
-
 Mycobacterium tuberculosis 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O step in mycothiol biosynthesis Mycobacterium tuberculosis 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O
-
 Mycobacterium tuberculosis H37Rv 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?
1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O step in mycothiol biosynthesis Mycobacterium tuberculosis H37Rv 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + acetate
-
 ?

Synonyms

Synonyms Comment Organism
MshB
-
 Mycobacterium tuberculosis
Rv1170
-
 Mycobacterium tuberculosis