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Literature summary for 3.4.25.1 extracted from
- Selective activation of the 20 S proteasome (multicatalytic proteinase complex) by histone H3 (2001), Biochemistry, 40, 15318-15326.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| histone H3 | slective activation of the branched-chain amino acid preferring activity with benzyloxycarbonyl-GPALG-4-aminobenzoate as substrate, 1000% | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| histone H3 | activity with benzyloxycarbonyl-LAF-4-aminobenzoate, 87%, benzyloxycarbonyl-dALR-4-aminobenzoate, 43%, or benzyloxycarbonyl-LLE-2-naphthylamide, 81% as substrates | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pituitary gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-dALR-2-naphthylamide + H2O | - |
Bos taurus | ? | - |
? |  |
| benzyloxycarbonyl-GPALG-4-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-LAF-4-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-LLE-2-naphthylamide + H2O | - |
Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 20S proteasome | - |
Bos taurus |
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