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Literature summary for 3.4.24.B9 extracted from

  • Mongaret, C.; Alexandre, J.; Thomas-Schoemann, A.; Bermudez, E.; Chereau, C.; Nicco, C.; Goldwasser, F.; Weill, B.; Batteux, F.; Lemare, F.
    Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form (2011), Int. J. Cancer, 129, 791-798.
    View publication on PubMed
Search for more literature for 3.4.24.B9

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
 x * 68000, secreted form of ADAM9, SDS-PAGE Homo sapiens
80000
-
 x * 80000, mature form of ADAM9, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 68000, secreted form of ADAM9, SDS-PAGE Homo sapiens
? x * 80000, mature form of ADAM9, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ADAM9
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens 3 h exposure to 1 mM H2O2 induces ADAM9 expression and ADAM-specific metalloprotease activity in A549 cells up

General Information

General Information Comment Organism
physiological function the enzyme is implicated in auto and paracrine regulation of invasiveness in A-549 cells Homo sapiens