Literature summary for 3.4.24.B7 extracted from

Lee, S.; Desai, K.K.; Iczkowski, K.A.; Newcomer, R.G.; Wu, K.J.; Zhao, Y.; Tan, W.W.; Roycik, M.D.; Sang, Q.A.
Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor (2006), Cell Res., 16, 750-758.

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Application

Application	Comment	Organism
medicine	MMP-26 may play an integral role during the conversion of HGPIN to invasive cancer and may also serve as marker for early prostate cancer diagnosis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
prostate cancer cell	malignant prostate tumor. Higher MMP-26 expression in high-grade prostatic intraepithelial neoplasia and cancer, compared to non-neoplastic acini. The expression level is highest in high-grade prostatic intraepithelial neoplasia, but declines in invasive cancer in the same tissue. MMP-26 may play an important role in the initial conversion of prostate cancer cells to an invasive phenotype	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-26	-	Homo sapiens

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Release 2023.1 (January 2023)