Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.B5 extracted from

  • Kaituu-Lino, T.J.; Palmer, K.; Tuohey, L.; Ye, L.; Tong, S.
    MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin (2012), PLoS ONE, 7, e39864.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme does not cleave endoglin ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P51511
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BeWo cell
-
Homo sapiens
-
HUVEC cell
-
Homo sapiens
-
placenta
-
Homo sapiens
-
syncytiotrophoblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme does not cleave endoglin Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MMP-15
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme is significantly up-regulated in placentas from severe early-onset preeclamptic pregnancies compared to gestationally matched preterm controls up