Literature summary for 3.4.24.B4 extracted from

Naito, S.; Takahashi, T.; Onoda, J.; Yamauchi, A.; Kawai, T.; Kishino, J.; Yamane, S.; Fujii, I.; Fukui, N.; Numata, Y.
Development of a neutralizing antibody specific for the active form of matrix metalloproteinase-13 (2012), Biochemistry, 51, 8877-8884.

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Application

Application	Comment	Organism
analysis	generation of a neutralizing antibody specifc for the active form of MMP-13, but not for the latent form, or other MMPs. antibody can be used to measure active MMP-13 selectively by an enzyme-linked immunosorbet assay. The antibody suppresses the cleavage of type II collagen in human articular chondrocyte cultures, and is thought to inhibit MMP-13 activity effectively	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P45452	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Homo sapiens	-

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Release 2023.1 (January 2023)