Literature summary for 3.4.24.B4 extracted from

Kim, K.S.; Oh, d.a..H.; Choi, H.M.; Bang, J.S.; Ryu, C.J.; Kim, J.H.; Yoo, M.C.; Yang, H.I.
Pyrrolidine dithiocarbamate, a NF-kappaB inhibitor, upregulates MMP-1 and MMP-13 in IL-1beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes (2009), Eur. J. Pharmacol., 613, 167-175.

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Cloned(Commentary)

Cloned (Comment)	Organism
MMP-13 expression analysis by semi-quantitative RTPCR	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
synoviocyte	interleukin-1beta-stimulated rheumatoid arthritis fibroblast-like, semi-quantitative RTPCR MMP-13 expression analysis	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
MMP-13	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	the NF-kappaB inhibitors fenofibrate, N-acetylcysteine and MG132 decrease MMP-13 expression in interleukin-1beta-stimulated fibroblast-like synoviocytes	down
Homo sapiens	pyrrolidine dithiocarbamate, a NF-kappaB inhibitor, upregulates MMP-1 and MMP-13 in interleukin-1beta-stimulated rheumatoid arthritis fibroblast-like synoviocytes in a stimuli-specific manner or by an NF-kappaB independent mechanism	up

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Release 2023.1 (January 2023)