Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P45452 | gene Mmp13 | - |
Mus musculus | - |
gene Mmp13 | - |
Mus musculus C57BL/6 | - |
gene Mmp13 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Mus musculus | - |
bone marrow | - |
Homo sapiens | - |
additional information | Mmp13 is expressed in human neovascular membranes | Homo sapiens | - |
additional information | Mmp13 is expressed in mouse choroidal neovascular lesions induced by laser burn | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
collagenase-3 | - |
Mus musculus |
collagenase-3 | - |
Homo sapiens |
MMP13 | a matrix metalloproteinase family member | Mus musculus |
MMP13 | a matrix metalloproteinase family member | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | MMP13 involvement in age-related macular degeneration | Homo sapiens |
additional information | potential role of MMP13 in choroidal angiogenesis in a murine model of laser-induced ocular neovascularisation. Deficiency of Mmp13 impaires choroidal neovascularization formation which is fully restored by wild-type bone marrow engraftment and partially rescued by several injections of wild-type mesenchymal stem cells. Mmp13 deficiency not only affects vessel recruitment, but also impairs their maturation through pericyte coverage | Mus musculus |