Literature summary for 3.4.24.B27 extracted from

Zhao, M.; Qiu, W.; Li, Y.; Sang, Q.; Wang, Y.
Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cells (2009), Sci. China C Life Sci., 52, 710-718.

Search for more literature for 3.4.24.B27

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
choriocarcinoma cell	in choriocarcinoma cell line JEG-3, the overexpression of ADAM19 leads to diminished cell invasion, as well as increases in cell adhesiveness and the expression of E-cadherin, with no changes in beta-catenin expression	Homo sapiens	-
placenta	ADAM19 is widely distributed in villous cytotrophoblast cells, syncytiotrophoblast cells, column trophoblasts, and villous capillary endothelial cells during early pregnancy. The mRNA and protein level of ADAM19 in placentas is high at gestational weeks 8-9, but diminishes significantly at mid- and term pregnancy	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ADAM19 endopeptidase	recommended name	Homo sapiens
adamalysin19	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	mRNA and protein level of ADAM19 in placentas diminishe significantly at mid- and term pregnancy	down
Homo sapiens	mRNA and protein level of ADAM19 in placentas is high at gestational weeks 8-9	up

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Release 2023.1 (January 2023)