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Literature summary for 3.4.24.B20 extracted from

  • Krynicka, V.; Tichy, M.; Krafl, J.; Yu, J.; Ka?a, R.; Boehm, M.; Nixon, P.J.; Komenda, J.
    Two essential FtsH proteases control the level of the Fur repressor during iron deficiency in the cyanobacterium Synechocystis sp. PCC 6803 (2014), Mol. Microbiol., 94, 609-624.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane FtsH1/FtsH3 complex Synechocystis sp.
-
-
thylakoid membrane FtsH1/FtsH3 complex Synechocystis sp. 42651
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fur repressor protein + H2O Synechocystis sp. degraded by the FtsH1/FtsH3 complex ?
-
?

Organism

Organism UniProt Comment Textmining
Synechocystis sp. P72991
-
-
Synechocystis sp. P73179
-
-
Synechocystis sp. P73437
-
-
Synechocystis sp. Q55700
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fur repressor protein + H2O degraded by the FtsH1/FtsH3 complex Synechocystis sp. ?
-
?

Subunits

Subunits Comment Organism
heterohexamer
-
Synechocystis sp.

Synonyms

Synonyms Comment Organism
FtsH1 subunit Synechocystis sp.
FtsH2 subunit Synechocystis sp.
FtsH3 subunit Synechocystis sp.
FtsH4 subunit Synechocystis sp.

General Information

General Information Comment Organism
malfunction a mutant conditionally depleted in FtsH3 is unable to induce normal expression of the IsiA chlorophyll-protein and FutA1 iron transporter upon iron deficiency due to a block in transcription, which is regulated by the Fur transcriptional repressor Synechocystis sp.
malfunction A stabilizing effect on Fur is observed in a mutant conditionally depleted in the FtsH1 subunit Synechocystis sp.
physiological function the FtsH1 protease is involved in the acclimation of cells to iron deficiency Synechocystis sp.
physiological function the FtsH2/FtsH3 complex is involved in photoprotection Synechocystis sp.
physiological function the FtsH2/FtsH3 complex is involved in photoprotection. The FtsH3 protease is involved in the acclimation of cells to iron deficiency Synechocystis sp.