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Literature summary for 3.4.24.B18 extracted from
- Maintenance of mitochondrial genome distribution by mitochondrial AAA+ protein ClpX (2012), Exp. Cell Res., 318, 2335-2343.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21 cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Homo sapiens | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ClpX | - |
Homo sapiens |
| mitochondrial AAA+ protein | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme knockdown in HeLa cells results in enlarged mitochondrial DNA nucleoids | Homo sapiens |
| physiological function | the enzyme maintains mitochondrial DNA nucleoid distribution through mitochondrial transcription factor A function as a chaperone rather than as a protease and is involvement in mitochondrial DNA segregation | Homo sapiens |
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Release 2023.1 (January 2023)
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