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Literature summary for 3.4.24.B18 extracted from
- Membrane protein turnover by the m-AAA protease in mitochondria depends on the transmembrane domains of its subunits (2004), EMBO Rep., 5, 698-703.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | deletion of either subunit Yta10 or Yta12, partial stabilization of substrate Atp7. Deletion of transmembrane segments of either subunit Yta10 or Yta12, enzyme retains proteolytic activity, but proteolsis of integral membrane proteins is impaired. Transmembrane segments of enzyme have a direct role in the dislocation of membrane-embedded subsrates | Saccharomyces cerevisiae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protein Atp7 + H2O | Saccharomyces cerevisiae | subunit of F1Fo-ATP synthase, peripheral membrane protein | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cytochrome c peroxidase + H2O | - |
Saccharomyces cerevisiae | ? | - |
? | |
| protein Atp7 + H2O | subunit of F1Fo-ATP synthase, peripheral membrane protein | Saccharomyces cerevisiae | ? | - |
? | |
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Release 2023.1 (January 2023)
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