Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Escherichia coli | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli W3110 / ATCC 27325 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | protein LpxC from A aeolicus is not degraded by FtsH from Escherichia coli | Escherichia coli | ? | - |
? | |
additional information | protein LpxC from A aeolicus is not degraded by FtsH from Escherichia coli | Escherichia coli W3110 / ATCC 27325 | ? | - |
? | |
protein LpxC + H2O | turnover of LpxC requires a length- and sequence-specific C-terminal degradation signal. LpxC proteins from Salmonella enterica, Yersinia pseudotuberculosis, and Vibrio cholerae are degraded with half-lives comparable to the half-life of Escherichia coli LpxC (8 to 12 min). LpxC from Pseudomonas aeruginosa is degraded slowly with a half-life of 78 min. LpxC proteins from Agrobacterium tumefaciens and Rhodobacter capsulatus are degraded with half-lives of about 68 min and 20 min, respectively | Escherichia coli | ? | - |
? | |
protein LpxC + H2O | turnover of LpxC requires a length- and sequence-specific C-terminal degradation signal. LpxC proteins from Salmonella enterica, Yersinia pseudotuberculosis, and Vibrio cholerae are degraded with half-lives comparable to the half-life of Escherichia coli LpxC (8 to 12 min). LpxC from Pseudomonas aeruginosa is degraded slowly with a half-life of 78 min. LpxC proteins from Agrobacterium tumefaciens and Rhodobacter capsulatus are degraded with half-lives of about 68 min and 20 min, respectively | Escherichia coli W3110 / ATCC 27325 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FtsH | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | FtsH controls lipopolysaccharide biosynthesis by proteolysis of LpxC | Escherichia coli |