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Literature summary for 3.4.24.B17 extracted from

  • Langklotz, S.; Schaekermann, M.; Narberhaus, F.
    Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria (2011), J. Bacteriol., 193, 1090-1097.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Escherichia coli 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli W3110 / ATCC 27325
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information protein LpxC from A aeolicus is not degraded by FtsH from Escherichia coli Escherichia coli ?
-
?
additional information protein LpxC from A aeolicus is not degraded by FtsH from Escherichia coli Escherichia coli W3110 / ATCC 27325 ?
-
?
protein LpxC + H2O turnover of LpxC requires a length- and sequence-specific C-terminal degradation signal. LpxC proteins from Salmonella enterica, Yersinia pseudotuberculosis, and Vibrio cholerae are degraded with half-lives comparable to the half-life of Escherichia coli LpxC (8 to 12 min). LpxC from Pseudomonas aeruginosa is degraded slowly with a half-life of 78 min. LpxC proteins from Agrobacterium tumefaciens and Rhodobacter capsulatus are degraded with half-lives of about 68 min and 20 min, respectively Escherichia coli ?
-
?
protein LpxC + H2O turnover of LpxC requires a length- and sequence-specific C-terminal degradation signal. LpxC proteins from Salmonella enterica, Yersinia pseudotuberculosis, and Vibrio cholerae are degraded with half-lives comparable to the half-life of Escherichia coli LpxC (8 to 12 min). LpxC from Pseudomonas aeruginosa is degraded slowly with a half-life of 78 min. LpxC proteins from Agrobacterium tumefaciens and Rhodobacter capsulatus are degraded with half-lives of about 68 min and 20 min, respectively Escherichia coli W3110 / ATCC 27325 ?
-
?

Synonyms

Synonyms Comment Organism
FtsH
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli

General Information

General Information Comment Organism
physiological function FtsH controls lipopolysaccharide biosynthesis by proteolysis of LpxC Escherichia coli