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Literature summary for 3.4.24.B17 extracted from

  • Shotland, Y.; Shifrin, A.; Ziv, T.; Teff, D.; Koby, S.; Kobiler, O.; Oppenheim, A.B.
    Proteolysis of bacteriophage lambda CII by Escherichia coli FtsH (HflB) (2000), J. Bacteriol., 182, 3111-3116.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
o-phenanthroline metal chelator Escherichia coli
phage lambda CIII protein enzyme participates in the phage lambda lysis-lysogeny decision by degrading the CII transcriptional activator and by its response to inhibition by the lambda CIII gene product Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phage lambda CII protein + H2O Escherichia coli enzyme participates in the phage lambda lysis-lysogeny decision by degrading the CII transcriptional activator and by its response to inhibition by the lambda CIII gene product small peptides
-
?
protein + H2O Escherichia coli degradation of regulatory proteins to control gene activity and metabolism peptides
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-casein + H2O
-
Escherichia coli small peptides of 13-20 amino acid residues product analysis ?
additional information no activity with bovine serum albumin Escherichia coli ?
-
?
phage lambda CII protein + H2O recombinant protein substrate with -terminal or C-terminal His-tag, respectively, or no His-tag Escherichia coli small peptides of 13-20 amino acid residues product analysis ?
phage lambda CII protein + H2O enzyme participates in the phage lambda lysis-lysogeny decision by degrading the CII transcriptional activator and by its response to inhibition by the lambda CIII gene product Escherichia coli small peptides
-
?
protein + H2O enzyme shows limited substrate specificity which is not primarily determined by the structure of the protein Escherichia coli peptides
-
?
protein + H2O degradation of regulatory proteins to control gene activity and metabolism Escherichia coli peptides
-
?

Synonyms

Synonyms Comment Organism
FtsH
-
Escherichia coli
HflB
-
Escherichia coli
M41.001 Merops-ID Escherichia coli

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
assay at Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP dependent on Escherichia coli