Cloned (Comment) | Organism |
---|---|
expression of wild-type and mutant from plasmid | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme mutant still shows activity with substrates derivative of the N-terminal domain of the lambdacI repressor tagged with cI105 and SsrA | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral, with the active site in the cytoplasm | Escherichia coli | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc protease | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein + H2O | Escherichia coli | tail specific pathway for removing abnormal cytoplasmic proteins via the enzyme, disposition by degradation of polypeptides synthesized from truncated mRNA molecules and are C-terminally tagged with an 11-amino-acid nonpolar destabilizing tail via a mechanism involving the 10Sa stable RNA | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0AAI3 | K12 derivatives, strain JM105 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme shows overlapping substrate specificity with the proteases C1pXP and C1pAP, the enzymes can compensate for each other in degrading the c1-SsrA tagged substrate protein | Escherichia coli | ? | - |
? | |
protein + H2O | - |
Escherichia coli | peptides | - |
? | |
protein + H2O | tail specific pathway for removing abnormal cytoplasmic proteins via the enzyme, disposition by degradation of polypeptides synthesized from truncated mRNA molecules and are C-terminally tagged with an 11-amino-acid nonpolar destabilizing tail via a mechanism involving the 10Sa stable RNA | Escherichia coli | peptides | - |
? | |
protein lambdaCII + H2O | regulatory protein | Escherichia coli | ? | - |
? | |
protein lambdaCIII + H2O | regulatory protein | Escherichia coli | ? | - |
? | |
protein sigma32 + H2O | heat shock factor | Escherichia coli | ? | - |
? | |
unstable derivatives of the N-terminal domain of the lambdacI repressor + H2O | 3 derivatives with a nonpolar pentapeptide tail, i.e. cI104, cI105, cI108, and 1 with the SsrAtag, i.e. cI-SsrA | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cell division protein ftsH | - |
Escherichia coli |
FtsH | - |
Escherichia coli |
FTSH_ECOLI | - |
Escherichia coli |
HflB | - |
Escherichia coli |
M41.001 | Merops-ID | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | dependent on | Escherichia coli |