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Literature summary for 3.4.24.B15 extracted from
- Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX (1997), FASEB J., 11, 355-364.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene PEX mapps to chromosome region Xp22.1 | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | bound | Homo sapiens | 16020 | - |
| additional information | enzyme is possibly an ectoenzyme, membrane-spanning region towards the N-terminus | Homo sapiens | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | zinc-metalloprotease | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protein + H2O | Homo sapiens | participates in postsecretory processing, enzyme is involved in regulation of phosphate levels and in bone metabolism | peptides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protein + H2O | - |
Homo sapiens | peptides | - |
? | |
| protein + H2O | participates in postsecretory processing, enzyme is involved in regulation of phosphate levels and in bone metabolism | Homo sapiens | peptides | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| M13.091 | Merops-ID | Homo sapiens |
| PEX | - |
Homo sapiens |
| vitamin D-resistant hypophosphatemic rickets protein | - |
Homo sapiens |
| X-linked hypophosphatemia protein | - |
Homo sapiens |
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