Literature summary for 3.4.24.B12 extracted from

Dancevic, C.M.; Gibert, Y.; Berger, J.; Smith, A.D.; Liongue, C.; Stupka, N.; Ward, A.C.; McCulloch, D.R.
The ADAMTS5 metzincin regulates zebrafish somite differentiation (2018), Int. J. Mol. Sci., 19, E766 .

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	dependent on	Danio rerio

Organism

Organism	UniProt	Comment	Textmining
Danio rerio	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	-	Danio rerio	-
forebrain	-	Danio rerio	-
mesendoderm	-	Danio rerio	-
neural tube	-	Danio rerio	-

Subunits

Subunits	Comment	Organism
?	x * 120000, SDS-PAGE	Danio rerio

Synonyms

Synonyms	Comment	Organism
a disintegrin and metalloproteinase with thrombospondin-1 motifs 5	-	Danio rerio
ADAMTS5	-	Danio rerio

General Information

General Information	Comment	Organism
malfunction	skeletal muscle formation is disrupted in enzyme-deficient embryos	Danio rerio
physiological function	the enzyme also plays an important non-enzymatic role in regulating the Sonic Hedgehog pathway during embryogenesis that impacts on muscle development	Danio rerio

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Release 2023.1 (January 2023)