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Literature summary for 3.4.24.B11 extracted from

  • Lee, N.V.; Sato, M.; Annis, D.S.; Loo, J.A.; Wu, L.; Mosher, D.F.; Iruela-Arispe, M.L.
    ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2 (2006), EMBO J., 25, 5270-5283.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.B11

Protein Variants

Protein Variants Comment Organism
E385A inactive Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
heparin heparin inhibits cleavage of thrombonspondin-2, but not thrombonspondin-1 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
87000
-
 full-length active ADAMTS1, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aggrecan + H2O
-
 Homo sapiens ?
-
 ?
additional information does not cleave laminin Homo sapiens ?
-
 ?
thrombospondin-1 + H2O
-
 Homo sapiens 36000 Da fragment + 110000 Da fragment
-
 ?
thrombospondin-2 + H2O
-
 Homo sapiens 42000 Da fragment + 30000 Da fragment
-
 ?

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase with thrombospondin 1
-
 Homo sapiens
ADAMTS1
-
 Homo sapiens