Literature summary for 3.4.24.87 extracted from

Yeh, H.C.; Zhou, Z.; Choi, H.; Tekeoglu, S.; May, W.; Wang, C.; Turner, N.; Scheiflinger, F.; Moake, J.L.; Dong, J.F.
Disulfide bond reduction of von Willebrand factor by ADAMTS-13 (2010), J. Thromb. Haemost., 8, 2778-2788.

Search for more literature for 3.4.24.87

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in CHO cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
von Willebrand factor + H2O	Homo sapiens	the disulfide-bond-reducing activity of ADAMTS-13 prevents covalent lateral association and increased platelet adherence of plasma-type von Willebrand factor multimers induced by high fluid shear stress	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA column chromatography	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
von Willebrand factor + H2O	the disulfide-bond-reducing activity of ADAMTS-13 prevents covalent lateral association and increased platelet adherence of plasma-type von Willebrand factor multimers induced by high fluid shear stress	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
a disintegrin and metalloprotease with thrombospondin type 1 repeats 13	-	Homo sapiens
ADAMTS-13	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)