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Literature summary for 3.4.24.87 extracted from

  • Taniguchi, S.; Hashiguchi, T.; Ono, T.; Takenouchi, K.; Nakayama, K.; Kawano, T.; Kato, K.; Matsushita, R.; Nagatomo, M.; Nakamura, S.; Nakashima, T.; Maruyama, I.
    Association between reduced ADAMTS13 and diabetic nephropathy (2010), Thromb. Res., 125, e310-e316.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of ADAMTS13 in HEK-293 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
diabetic patients and healthy persons
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
Homo sapiens
von Willebrand factor-cleaving protease
-
Homo sapiens
vWF-cleaving protease
-
Homo sapiens

General Information

General Information Comment Organism
additional information association between reduced plasma ADAMTS13 antigen levels and diabetic nephropathy, with a significant positive and negative correlation between ADAMTS13 antigen and the estimated glomerular filtration rate, and von Willebrand factor/ADAMTS13 ratio, respectively, imunohistochemic analysis, overview Homo sapiens