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Literature summary for 3.4.24.87 extracted from

  • Zheng, X.
    ADAMTS13 testing: Why bother? (2010), Blood, 115, 1475-1476.
    View publication on PubMed
Search for more literature for 3.4.24.87

Application

Application Comment Organism
diagnostics role for clinical testing of plasma ADAMTS13 activity and inhibitors in care of thrombotic thrombocytopenic purpura patients, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
FRETS-vWF73 + H2O a fluorogenic von Willebrand factor-derived peptide substrate Homo sapiens ?
-
 ?
von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
 Homo sapiens

General Information

General Information Comment Organism
additional information a lower level of initial plasma ADAMTS13 activity is associated with higher risk of relapse in patients with thrombotic thrombocytopenic purpura. Also, patients with a low plasma ADAMTS13 activity and high titer inhibitor appear to have lower survival rate, overview Homo sapiens
physiological function ADAMTS13 is involved in thrombotic thrombocytopenic purpura Homo sapiens