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Literature summary for 3.4.24.87 extracted from

  • de Mast, Q.; Groot, E.; Asih, P.B.; Syafruddin, D.; Oosting, M.; Sebastian, S.; Ferwerda, B.; Netea, M.G.; de Groot, P.G.; van der Ven, A.J.; Fijnheer, R.
    ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria (2009), Am. J. Trop. Med. Hyg., 80, 492-498.
    View publication on PubMed
Search for more literature for 3.4.24.87

Protein Variants

Protein Variants Comment Organism
P475S the common naturally occuring polymorphsim is not involved in ADAMTS13 inhibition in malaria patients Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information malaria patients possess high ADAMTS13 autoantibodies levels as well as endogenous ADAMTS13 inhibitors compared to healthy controls Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Homo sapiens
-
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
 Homo sapiens
von Willebrand factor cleaving protease
-
 Homo sapiens
VWF cleaving protease
-
 Homo sapiens

General Information

General Information Comment Organism
additional information ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor caused by Plasmodium falciparum and Plasmodium vivax malaria, overview Homo sapiens