Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.87 extracted from

  • Lam, J.K.; Chion, C.K.; Zanardelli, S.; Lane, D.A.; Crawley, J.T.
    Further characterization of ADAMTS-13 inactivation by thrombin (2007), J. Thromb. Haemost., 5, 1010-1018.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information proteolysis of ADAMTS-13 by thrombin leads to a 8fold reduction in affinity for von Willebrand factor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase with a thrombonspondin type 1 motif member 13
-
Homo sapiens
ADAMTS-13
-
Homo sapiens