Application | Comment | Organism |
---|---|---|
medicine | description of a simple procedure to analyse the kinetics of von Willebrand factor proteolysis that is suitable for routine diagnostic use | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ba2+ | complete proteolysis is observed at 37°C in the presence of BaCl2 while about 25% von Willebrand factor still binds to collagen when BaCl2 supplementation is omitted | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | platelet-poor | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | complete proteolysis is observed at 37°C in the presence of BaCl2 while about 25% von Willebrand factor still binds to collagen when BaCl2 supplementation is omitted. Proteolysis kinetics at 22°C and 4°C is slower but complete | Homo sapiens | 2 peptides of 140 kDa and 176 kDa | - |
? |