Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.86 extracted from

  • Malapeira, J.; Esselens, C.; Bech-Serra, J.; Canals, F.; Arribas, J.
    ADAM17 (TACE) regulates TGFbeta signaling through the cleavage of vasorin (2011), Oncogene, 30, 1912-1922.
    View publication on PubMed
Search for more literature for 3.4.24.86

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
vasorin + H2O Homo sapiens
-
 soluble vasorin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
vasorin + H2O
-
 Homo sapiens soluble vasorin + ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAM17
-
 Homo sapiens
TACE
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction inhibition of ADAM17 leads to the upregulation of transforming growth factor-beta signaling Homo sapiens
physiological function through the cleavage of vasorin, ADAM17 controls transforming growth factor-beta-mediated epithelial-to-mesenchymal transition Homo sapiens