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Literature summary for 3.4.24.86 extracted from

  • Lee, J.H.; Choi, Y.J.; Heo, S.H.; Lee, J.M.; Cho, J.Y.
    Tumor necrosis factor-alpha converting enzyme (TACE) increases RANKL expression in osteoblasts and serves as a potential biomarker of periodontitis (2011), BMB Rep., 44, 473-477.
    View publication on PubMed
Search for more literature for 3.4.24.86

Application

Application Comment Organism
medicine the enzyme serves as a potential biomarker of periodontitis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gingiva
-
 Homo sapiens
-
gingival fluid
-
 Homo sapiens
-
osteoblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
proTNF-alpha + H2O
-
 Homo sapiens soluble TNF-alpha
-
 ?

Synonyms

Synonyms Comment Organism
ADAM17
-
 Homo sapiens
TACE
-
 Homo sapiens
TNF-alpha converting enzyme
-
 Homo sapiens
tumor necrosis factor-alpha converting enzyme
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme increases receptor activator of nuclear factor-kappaB ligand secretion and decreases osteoprotegerin protein expression in osteoblasts Homo sapiens