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Literature summary for 3.4.24.86 extracted from

  • Li, X.; Yan, Y.; Huang, W.; Yang, Y.
    The study of the inhibition of the recombinant TACE prodomain to endotoxemia in mice (2009), Int. J. Mol. Sci., 10, 5442-5454.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine treatment of mice in a lipopolysaccharide-induced endotoxemia model group with recombinant TACE prodomain protein prior to the injection of lipopolysaccharide. The recombinant prodomain protein decreases the release of the secreted TNF-alpha, which mediates the accumulation of TNF-alpha on the surface of macrophage cells. The recombinant protein can decrease the inflammatory response in internal organs of endotoxaemia mice Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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