Application | Comment | Organism |
---|---|---|
molecular biology | TACE/ADAM17-like proteases might play a role in synaptic formation to generate specific neuronal connections by processing the excess amount of RA175/SynCAM1, a member of the immunoglobulin family 4, located in the non-synaptic region | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
TAPI-1 | TAPI-1 blocks the processing of RA175/SynCAM1, a member of the immunoglobulin family 4. Furthermore, TAPI-1 increases the number of synaptophysin and RA175/SynCAM1 colocalization on the dendrites of neurons | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RA175/SynCAM1 + H2O | Mus musculus | neuronal RA175/SynCAM1 isoforms, members of the immunoglobulin family 4, are processed by TACE | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
RA175/SynCAM1 + H2O | neuronal RA175/SynCAM1 isoforms, members of the immunoglobulin family 4, are processed by TACE | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TACE | - |
Mus musculus |