Application | Comment | Organism |
---|---|---|
medicine | existence of a checkpoint response activated by the nuclear abnormalities caused by prelamin A accumulation, hyperactivation of the tumour suppressor p53 may cause accelerated ageing | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | Zmste24-deficient mice, Zmpste24 deficiency elicits a stress signaling pathway that is evidenced by a marked upregulation of p53 target genes, accompanied by a senescence phenotype at the cellular level and accelerated ageing at the organismal level | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
FACE-1 | - |
Mus musculus |
Zmpste24 | - |
Mus musculus |