Any feedback?
Literature summary for 3.4.24.83 extracted from
- Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein (2009), PLoS ONE, 4, e7946.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | anthrax toxin entry and activity differs among immune cells. Macrophages, dendritic cells, and B cells display higher activity of a of fusion protein of the anthrax toxin lethal factor N-terminal domain LFn, residues 1-254, with beta-lactamase, i.e. LFnBLA, than CD4+ and CD8+ T cells in both spleen cell suspension and the purified samples of individual cell types. Expression of anthrax toxin receptor CMG2 is higher in CD4+ and CD8+ T cells, which is not correlated to the intracellular LFnBLA activity | Bacillus anthracis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of fusion protein of the anthrax toxin lethal factor N-terminal domain LFn, residues 1-254, with beta-lactamase | Bacillus anthracis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus anthracis | - |
- |
- |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
