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Literature summary for 3.4.24.83 extracted from

  • Ngai, S.; Batty, S.; Liao, K.C.; Mogridge, J.
    An anthrax lethal factor mutant that is defective at causing pyroptosis retains proapoptotic activity (2010), FEBS J., 277, 119-127.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
K518E/E682G mutation in anthrax lethal factor, mutant is defective at causing pyroptosis in RAW 264.7 cells and at activating the Nlrp1b inflammasome in a heterologous expression system. LF-K518E /E682G does not exhibit an overall impairment of function and LF-K518E /E682G efficiently kills melanoma cells Bacillus anthracis

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
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Source Tissue

Source Tissue Comment Organism Textmining