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Literature summary for 3.4.24.82 extracted from
- Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites (2000), J. Biol. Chem., 275, 38885-38890.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of cDNA in COS-7 cells | Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 69000 | - |
x * 69000, recombinant aggrecanase-1, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O75173 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| glioma cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| brevican + H2O | recombinantrat brevican, recombinant aggrecanase-1 most probably cleaves at Glu395-Ser396 | Homo sapiens | fragments of brevican | - |
? |  |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 69000, recombinant aggrecanase-1, SDS-PAGE | Homo sapiens |
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Release 2023.1 (January 2023)
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