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Literature summary for 3.4.24.81 extracted from

  • Franzke, C.W.; Bruckner-Tuderman, L.; Blobel, C.P.
    Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9 (2009), J. Biol. Chem., 284, 23386-23396.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
GI254023X ADAM10-selective inhibitor Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen XVII/BP180 + H2O Mus musculus ADAM9 and ADAM10 are the most prominent collagen XVII sheddases in primary keratinocytes ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte ADAMs9 and 10 are the most prominent collagen XVII sheddases in primary keratinocytes Mus musculus
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skin
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen XVII/BP180 + H2O ADAM9 and ADAM10 are the most prominent collagen XVII sheddases in primary keratinocytes Mus musculus ?
-
?