Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-amyloid precursor protein | Homo sapiens | A172 cell line has alpha-secretase activity | sAPP-alpha fragment + C-terminal fragment | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
cell line | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-172 cell | A-172 cell line has potent alpha-secretase activity, higher than HEK-293 cell line | Homo sapiens | - |
bone marrow | there is expression of the enzyme | Homo sapiens | - |
brain | there is expression of the enzyme | Homo sapiens | - |
kidney cell line | there is expression of the enzyme | Homo sapiens | - |
liver | there is expression of the enzyme | Homo sapiens | - |
lymph node | there is expression of the enzyme | Homo sapiens | - |
spleen | there is expression of the enzyme | Homo sapiens | - |
thymus | there is expression of the enzyme | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-amyloid precursor protein | A172 cell line has alpha-secretase activity | Homo sapiens | sAPP-alpha fragment + C-terminal fragment | - |
? |