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Literature summary for 3.4.24.80 extracted from

  • Arroyo, A.G.; Genis, L.; Gonzalo, P.; Matias-Roman, S.; Pollan, A.; Galvez, B.G.
    Matrix metalloproteinases: new routes to the use of MT1-MMP as a therapeutic target in angiogenesis-related disease (2007), Curr. Pharm. Des., 13, 1787-1802.
    View publication on PubMed
Search for more literature for 3.4.24.80

Application

Application Comment Organism
medicine therapeutic target in angiogenesis-related disease Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in breast adenocarcinoma cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
N4-hydroxyamino-2-isobutyl-3-(thienylthiomethyl) succinyl]-L-phenylalamine-methylamide
-
 Homo sapiens
reversion-inducing-cysteine-rich protein
-
 Homo sapiens
TIMP-2
-
 Homo sapiens
TIMP-3
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein glycosylation and palmitoylation of Cys 564 in the cytosolic tail Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aggrecan + H2O
-
 Homo sapiens ?
-
 ?
alpha1-proteinase inhibitor + H2O
-
 Homo sapiens ?
-
 ?
alpha2-macroglobulin + H2O
-
 Homo sapiens ?
-
 ?
alpha5 integrin + H2O
-
 Homo sapiens ?
-
 ?
CD44 + H2O
-
 Homo sapiens ?
-
 ?
entactin + H2O
-
 Homo sapiens ?
-
 ?
fibrillin + H2O
-
 Homo sapiens ?
-
 ?
Fibrin + H2O
-
 Homo sapiens ?
-
 ?
Fibrinogen + H2O
-
 Homo sapiens ?
-
 ?
Gelatin + H2O
-
 Homo sapiens ?
-
 ?
gelsolin + H2O
-
 Homo sapiens ?
-
 ?
KiSS-1/metastin + H2O
-
 Homo sapiens ?
-
 ?
Laminin + H2O
-
 Homo sapiens ?
-
 ?
MCP-3/CCL7 + H2O
-
 Homo sapiens ?
-
 ?
pericentrin + H2O
-
 Homo sapiens ?
-
 ?
pro-matrix metalloproteinase-13 + H2O activation Homo sapiens ?
-
 ?
pro-matrix metalloproteinase-8 + H2O activation Homo sapiens ?
-
 ?
pro-tissue necrosis factor alpha + H2O
-
 Homo sapiens ?
-
 ?
pro-transforming growth factor beta + H2O
-
 Homo sapiens ?
-
 ?
progelatinase A + H2O activation, gelatinase A is matrix metalloproteinase-2 Homo sapiens gelatinase A + ?
-
 ?
SDF-1/CXCL12 + H2O
-
 Homo sapiens ?
-
 ?
syndecan + H2O
-
 Homo sapiens ?
-
 ?
tissue transglutaminase + H2O
-
 Homo sapiens ?
-
 ?
Type I collagen + H2O
-
 Homo sapiens ?
-
 ?
type II collagen + H2O
-
 Homo sapiens ?
-
 ?
type III collagen + H2O
-
 Homo sapiens ?
-
 ?
Vitronectin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
membrane type 1-matrix metalloproteinase
-
 Homo sapiens
MT1-MMP
-
 Homo sapiens