Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytokine | protein levels of the enzyme significantly increase by FGF-2 plus VEGF-A, only slightly by FGF-1, and not at all by VEGF-A | Bos taurus |
Application | Comment | Organism |
---|---|---|
medicine | endothelial cell invasion of collagen I gels is MT1-MMP dependent | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
anti-membrane-type 1-MMP antibody | antibodies LEM-1 and LEM-2 inhibit endothelial cell invasion in a dose dependent manner | Bos taurus | |
BB94 | inhibits endothelial cell invasion | Bos taurus | |
CT1399 | inhibits endothelial cell invasion | Bos taurus | |
CT1847 | inhibits endothelial cell invasion | Bos taurus | |
additional information | TIMP-1 does not inhibit endothelial cell invasion | Bos taurus | |
TIMP-2 | inhibits endothelial cell invasion | Bos taurus | |
TIMP-3 | inhibits endothelial cell invasion | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta endothelium | - |
Bos taurus | - |
Synonyms | Comment | Organism |
---|---|---|
membrane type 1 MMP | - |
Bos taurus |
MT1-MMP | - |
Bos taurus |