Application | Comment | Organism |
---|---|---|
medicine | the effect of smoking on three first trimester screening markers for Downs syndrome that constitute the Combined test, namely nuchal translucency (NT), PAPP-A and free beta human chorionic gonadotophin is examined. In addition it is determined which of these markers need to be adjusted for smoking and by how much. The effect of adjusting for smoking on the Combined test is small, with an estimated less than 0.5% increase in the detection rate for a 3% false-positive rate and less than 0.2% decrease in the false-positive rate for an 85% detection rate | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PAPP-A | - |
Homo sapiens |
pregnancy-associated plasma protein-A | - |
Homo sapiens |