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Literature summary for 3.4.24.79 extracted from

  • Joaquin, C.; Aguilera, E.; Granada, M.L.; Pastor, M.C.; Salinas, I.; Alonso, N.; Sanmarti, A.
    Effects of GH treatment in GH-deficient adults on adiponectin, leptin and pregnancy-associated plasma protein-A (2008), Eur. J. Endocrinol., 158, 483-490.
    View publication on PubMed
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Application

Application Comment Organism
medicine PAPP-A levels in adults with growth hormone deficiency at baseline and after growth hormone replacement is evaluated: 14 growth hormone deficiency adults are evaluated at baseline and after 1 year of growth hormone therapy. All patients are compared at baseline with 28 age-, sex- and body mass index (BMI)-matched control subjects. At baseline, growth hormone deficiency adults show higher PAPP-A levels and higher leptin, fibrinogen and highly sensitive C-reactive protein values than controls. Therapy with growth hormone reduces PAPP-A and fibrinogen levels while increased BMI and reduced waist-hip ratio are observed Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
blood
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
PAPP-A
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 Homo sapiens
pregnancy-associated plasma protein-A
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 Homo sapiens