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Literature summary for 3.4.24.79 extracted from

  • Hajek, P.; Macek, M.; Hladikova, M.; Houbova, B.; Alan, D.; Durdil, V.; Fiedler, J.; Maly, M.; Ostadal, P.; Veselka, J.; Krebsova, A.
    Pregnancy-associated plasma protein A and proform eosinophilic major basic protein in the detection of different types of coronary artery disease (2008), Physiol. Res., 57, 23-32.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
proform of eosinophil major basic protein i.e. proMBP, complex formation with PAPP-A Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in coronary artery disease, e.g. angina pectoris or acute myocardia infarction, independent of gender or age, PAPP-A/proMBP levels do not correlate with cardiac troponin I in patients, the PAPP-A/proMBP complex is involved in processes preceding vulnerable plaque development in acute coronary syndrome, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
artery coronary Homo sapiens
-
blood
-
Homo sapiens
-
heart
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
enzyme activity and enzyme-inhibitor complex levels in healthy persons and patients with coronary disease, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in coronary artery disease, e.g. angina pectoris or acute myocardia infarction, independent of gender or age, PAPP-A/proMBP levels do not correlate with cardiac troponin I in patients, the PAPP-A/proMBP complex is involved in processes preceding vulnerable plaque development in acute coronary syndrome, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PAPP-A
-
Homo sapiens
pregnancy-associated plasma protein-A
-
Homo sapiens