General Stability | Organism |
---|---|
high salt condition, SDS, or beta-mercaptoethanol inhibit | Homo sapiens |
Triton X-100, Tween-20, NP-40, sodium azide, glycerol do not affect enzyme activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
beta-mercaptoethanol | - |
Homo sapiens | |
SDS | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | secreted | Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | Zn2+ binding metalloprotease | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
400000 | - |
more than, gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
insulin-like growth factor binding protein-4 + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Storage Stability | Organism |
---|---|
-30°C, 1 year, no loss of activity | Homo sapiens |
4°C, 3 days, no loss of activity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
insulin-like growth factor binding protein-4 + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | cleavage of insulin-like growth factor binding protein-4 occurs only in presence of insulin-like growth factor-II | Homo sapiens | ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
10 min, no loss of activity | Homo sapiens |
55 | - |
10 min, no loss of activity | Homo sapiens |
70 | 95 | 10 min, complete inactivation | Homo sapiens |