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Literature summary for 3.4.24.79 extracted from

  • Lawrence, J.B.; Oxvig, C.; Overgaard, M.T.; Sottrup-Jensen, L.; Gleich, G.J.; Hays L.G.; Yates, J.R.3rd; Conover, C.A.
    The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A (1999), Proc. Natl. Acad. Sci. USA, 96, 3149-3153.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.79

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble secreted Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
400000
-
 nonreducing SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13219
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Renatured (Commentary)

Renatured (Comment) Organism
microdialysis against water reverses high salt inhibition Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin-like growth factor binding protein-4 + H2O
-
 Homo sapiens ?
-
 ?
insulin-like growth factor binding protein-4 + H2O
-
 Homo sapiens ? is cleaved into a 14 kDa and a 18 kDa fragment ?

Subunits

Subunits Comment Organism
dimer 2 x 200000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens