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Literature summary for 3.4.24.75 extracted from

  • Hertlein, T.; Sturm, V.; Lorenz, U.; Sumathy, K.; Jakob, P.; Ohlsen, K.
    Bioluminescence and 19F magnetic resonance imaging visualize the efficacy of lysostaphin alone and in combination with oxacillin against Staphylococcus aureus in murine thigh and catheter-associated infection models (2014), Antimicrob. Agents Chemother., 58, 1630-1638.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine lysostaphin exerts high levels of activity against antibiotic-resistant strains of Staphylococcus aureus Staphylococcus simulans

Cloned(Commentary)

Cloned (Comment) Organism
expressed as mature lysostaphin free from preprolysostaphin and prolysostaphin in Escherichia coli Staphylococcus simulans

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloprotease Staphylococcus simulans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
peptidoglycan + H2O Staphylococcus simulans
-
?
-
?

Organism

Organism UniProt Comment Textmining
Staphylococcus simulans P10547
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
peptidoglycan + H2O
-
Staphylococcus simulans ?
-
?

Synonyms

Synonyms Comment Organism
r-lysostaphin
-
Staphylococcus simulans