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Literature summary for 3.4.24.73 extracted from

  • Laing, G.D.; Moura-da-Silva, A.M.
    Jararhagin and its multiple effects on hemostasis (2005), Toxicon, 45, 987-996.
    View publication on PubMed
Search for more literature for 3.4.24.73

Inhibitors

Inhibitors Comment Organism Structure
BJ46a SVMP inhibitor forming a monovalent complex with jararhagin thus inhibiting its hemorrhagic and catalytic activities Bothrops jararaca
DM 43 SVMP inhibitor isolated from the venom of Didelphis marsupialis forming stable complexes with jararhagin thus inhibiting its hemorrhagic, fibrinolytic and proteolytic activities Bothrops jararaca
additional information no inhibition by alpha2-macroblobulin Bothrops jararaca
PO41 SVMP inhibitor isolated from the venom of Philander opossum forming stable complexes with jararhagin thus inhibiting its hemorrhagic, fibrinolytic and proteolytic activities Bothrops jararaca

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 jararhagin-C Bothrops jararaca
47000
-
 calculation from amino acid sequence, deduced from mature jararhagin Bothrops jararaca
52000
-
 SDS-PAGE, full-size jararhagin Bothrops jararaca

Organism

Organism UniProt Comment Textmining
Bothrops jararaca
-
 pit viper
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha2 subunit I domain of the platelet surface alpha2beta1 integrin + H2O
-
 Bothrops jararaca ?
-
 ?
Fibrinogen + H2O
-
 Bothrops jararaca ?
-
 ?

Synonyms

Synonyms Comment Organism
jararhagin-c consists of the disintegrin-like and cysteine-rich domains of jararhagin only Bothrops jararaca
soluble haemorrhagic snake venom metalloproteinase
-
 Bothrops jararaca
SVMP
-
 Bothrops jararaca

pI Value

Organism Comment pI Value Maximum pI Value
Bothrops jararaca
-
-
 4.5