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Literature summary for 3.4.24.71 extracted from
- Endothelin-converting enzyme-1 expression in acute and chronic liver injury in fibrogenesis (2019), Anim. Cells Sys., 23, 170-175 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| big endothelin-1 + H2O | Rattus norvegicus | - |
endothelin-1 + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | P42893 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| big endothelin-1 + H2O | - |
Rattus norvegicus | endothelin-1 + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ECE-1 | - |
Rattus norvegicus |
| endothelin-converting enzyme-1 | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | the mRNA expression of isoforms ECE-1a and -b is upregulated in biliary cirrhosis and in CCl4-injured livers, whereas isoform ECE-1c mRNA remains unchanged. Enzyme activity is increased after bile duct occlusion and peaks at 12 h after acute CCl4-intoxication | up |
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