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Literature summary for 3.4.24.71 extracted from

  • Whyteside, A.; Turner, A.; Lambert, D.
    Endothelin-converting enzyme-1 (ECE-1) is post-transcriptionally regulated by alternative polyadenylation (2014), PLoS ONE, 9, e83260.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
big endothelin-1 + H2O Homo sapiens
-
endothelin-1 + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P42892
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Huh-7 cell
-
Homo sapiens
-
PC-3 cell
-
Homo sapiens
-
prostate gland epithelium
-
Homo sapiens
-
RWPE-1 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
big endothelin-1 + H2O
-
Homo sapiens endothelin-1 + ?
-
?

Synonyms

Synonyms Comment Organism
ECE-1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is markedly inhibited by its 3'-untranslated region down
Homo sapiens alternative polyadenylation results in the production of enzyme transcripts with truncated 3'-untranslated regions which promote elevated protein expression up