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Literature summary for 3.4.24.71 extracted from

  • Buehler, K.; Ufer, M.; Mueller-Marbach, A.; Brinkmann, U.; Laule, M.; Stangl, V.; Roots, I.; Stangl, K.; Cascorbi, I.
    Risk of coronary artery disease as influenced by variants of the human endothelin and endothelin-converting enzyme genes (2007), Pharmacogenet. Genomics, 17, 77-83.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and anaylsis, genotyping, the ECE encoding gene shows several single nucleotide polymorphisms, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
K198N naturally occuring polymorphism, the mutant shows impaired function Homo sapiens
additional information the ECE encoding gene shows polymorphisms, genotyping, overview Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
additional information metalloendopeptidase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme plays a crucial role in the regulation of vascular tone and endothelial function ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme plays a crucial role in the regulation of vascular tone and endothelial function Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ECE-1
-
Homo sapiens
endothelin-converting enzyme-1
-
Homo sapiens