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Literature summary for 3.4.24.7 extracted from

  • Sudbeck, H.D.; Jeffrey, J.J.; Welgus, H.G.; Mecham, R.P.; McCourt, D.; Parks, W.C.
    Purification and characterization of bovine interstitial collagenase and tissue inhibitor metalloproteinases (1992), Arch. Biochem. Biophys., 293, 370-376.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0002
-
bovine type I collagen
-
Bos taurus
0.0005
-
human type I collagen
-
Bos taurus
0.0008
-
human type I collagen
-
Homo sapiens
0.0009
-
human type I collagen
-
Rattus norvegicus
0.001
-
human type II collagen
-
Bos taurus
0.0011
-
human type I collagen
-
Rattus norvegicus
0.0013
-
human type III collagen
-
Homo sapiens
0.0017
-
human type III collagen
-
Rattus norvegicus
0.0021
-
human type II collagen
-
Homo sapiens
0.0024
-
human type III collagen
-
Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
skin
-
Rattus norvegicus
-
skin
-
Bos taurus
-
skin from the lateral thoracic area of a 230 day fetal calf Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bovine type I collagen + H2O
-
Bos taurus ?
-
?
human type I collagen + H2O
-
Homo sapiens ?
-
?
human type I collagen + H2O
-
Rattus norvegicus ?
-
?
human type I collagen + H2O
-
Bos taurus ?
-
?
human type II collagen + H2O
-
Homo sapiens ?
-
?
human type II collagen + H2O
-
Rattus norvegicus ?
-
?
human type II collagen + H2O
-
Bos taurus ?
-
?
human type III collagen + H2O
-
Homo sapiens ?
-
?
human type III collagen + H2O
-
Rattus norvegicus ?
-
?
human type III collagen + H2O
-
Bos taurus ?
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.000267
-
human type II collagen
-
Homo sapiens
0.000383
-
human type II collagen
-
Rattus norvegicus
0.00147
-
bovine type I collagen
-
Bos taurus
0.0035
-
human type I collagen
-
Bos taurus
0.00375
-
human type I collagen
-
Rattus norvegicus
0.00392
-
human type II collagen
-
Rattus norvegicus
0.0056
-
human type III collagen
-
Homo sapiens
0.0148
-
human type I collagen
-
Homo sapiens
0.0958
-
human type III collagen
-
Bos taurus
0.153
-
human type III collagen
-
Homo sapiens