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Literature summary for 3.4.24.7 extracted from
- Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase (1987), J. Biol. Chem., 262, 6221-6226.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.8 | - |
type I collagen | - |
Homo sapiens | |
| 2.4 | - |
GPQGIAGT | - |
Homo sapiens |  |
| 2.8 | - |
GPQGLAGQ | - |
Homo sapiens | |
| 3.3 | - |
GPQGIAGQ | - |
Homo sapiens | |
| 3.6 | - |
GPLGIAGQ | - |
Homo sapiens | |
| 3.6 | - |
GPQGIAGA | - |
Homo sapiens | |
| 4.9 | - |
GPVGIAGQ | - |
Homo sapiens | |
| 5.6 | - |
GPRGIAGQ | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | fibroblasts | Homo sapiens | - |
| skin | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Collagen + H2O | rat tendon type I collagen | Homo sapiens | ? | - |
? | |
| GAQGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GLQGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GNQGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GP-Hyp-GIAGA + H2O | - |
Homo sapiens | ? | - |
? | |
| GP-Hyp-IAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPDGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPLGIAGP + H2O | - |
Homo sapiens | ? | - |
? | |
| GPLGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGIAGA + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGIAGH + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGIAGP + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGIAGT + H2O | - |
Homo sapiens | ? | - |
? | |
| GPQGLAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPRGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
| GPVGIAGQ + H2O | - |
Homo sapiens | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00278 | - |
type I collagen | - |
Homo sapiens | |
| 0.0717 | - |
GPRGIAGQ | - |
Homo sapiens | |
| 0.15 | - |
GPVGIAGQ | - |
Homo sapiens | |
| 0.203 | - |
GPQGIAGQ | - |
Homo sapiens | |
| 0.217 | - |
GPQGIAGA | - |
Homo sapiens | |
| 0.263 | - |
GPQGIAGT | - |
Homo sapiens | |
| 0.27 | - |
GPQGLAGQ | - |
Homo sapiens | |
| 0.333 | - |
GPLGIAGQ | - |
Homo sapiens | |
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