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Literature summary for 3.4.24.7 extracted from
- Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing (2004), Scand. J. Gastroenterol., 39, 1095-1104.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | MMP-1 is involved in intestinal re-epithelization in vivo and is upregulated by cytokines relevant in wound repair | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Caco-2 cell | MMP-1 is upregulated by TGF-beta, EGF and IL-1beta | Homo sapiens | - |
| enterocyte | MMP-1 is expressed by migrating enterocytes bordering intestinal ulcers. In the fetal gut model, MMP-1 expression by migrating enterocytes is detected | Homo sapiens | - |
| WiDr cell | MMP-1 is upregulated by EGF | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | MMP-1 is involved in intestinal re-epithelization in vivo and is upregulated by cytokines relevant in wound repair | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| collagenase-1 | - |
Homo sapiens |
| MMP-1 | - |
Homo sapiens |
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